Procurement comparison
TB-4 Research Optimization Tips: Peptide Comparison
TB-4 (Native) 4963 2–3 hours 2–8°C, 28 days max G-actin sequestration, inhibits actin polymerisation Wound healing, angiogenesis, cardiac repair Most bioactive native form but requires twice-daily dosing due to short half-life. Aggregation-prone during storage
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- TB-4 (Native)
- 4963
- 2–3 hours
- 2–8°C, 28 days max
- G-actin sequestration, inhibits actin polymerisation
- Wound healing, angiogenesis, cardiac repair
- Most bioactive native form but requires twice-daily dosing due to short half-life. Aggregation-prone during storage
- TB-500 (Synthetic)
- ~4963 (acetylated)
- 6–8 hours
- 2–8°C, 45+ days
- G-actin sequestration (acetylated stability)
- Extended-release wound studies
- Longer half-life allows once-daily dosing. Chemically stabilised structure reduces handling sensitivity
- BPC-157
- 1419
- 4+ hours
- 2–8°C, 30 days
- VEGF upregulation, nitric oxide modulation
- GI repair, tendon healing
- Stable across broader pH range (5.5–8.0). Complementary to TB-4 in multi-peptide protocols
- GHK-Cu
- 340 (peptide)
- 1–2 hours (copper-bound longer)
- 2–8°C, 14 days
- Copper delivery, collagen synthesis
- Dermal repair, anti-inflammatory models
- Copper chelation extends half-life but limits dosing frequency. Oxidises faster than non-chelated peptides